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Somedays I Just... 3 (3:02)


Somedays I just...

Wrote one more! Tuesday morning. Took till late night before I got to recording though... and I wasn't too happy with the result. So, I recorded it again today, along with adlibs... but maybe the first version was better after all hmm. You be the judge! I call them Stubble and Smooth, in order of Old and New. Lyrics here.

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  1. S3C
    Thursday Nov/19/2015

    I think this one has the best flow and lyrics...and no a single gene isn't responsible for aging, it's more complicated than that (and still largely unknown)...

    though you may be thinking of the enzyme telomerase, which is often implicated in being the driving factor behind senescence. But anyhow the telomerase enzyme is comprised of several proteins that comes from several genes. the point of telomerase is to elongate our DNA. why does it need our DNA need to be longer? because in eukaryotic (multi cellular organisms) each time our cells replicate the DNA shortens a bit. DNA that we need to function. So telomerase packs the useful DNA with 'junk' DNA at the end (called telomeres) that protects the important DNA from degrading each time our cells divide. So a theory is that if we have longer telomeres we will live longer. And thus, it's been proposed that a telomerase-like supplement could be used as an anti-aging agent.

    But when telomerase is overactivated, cells can continue to grow and divide in an unregulated fashion (hence cancer) and be considered biologically immortal(https://en.wikipedia.org/wiki/Immortalised_cell_line). There are laboratories that contain cancer cells from patients from several decades ago, and will survive indefinitely given the proper growth medium (glucose/dextrose and a saline solution I'd presume). But again referring back to what makes a telomere- it's just junk DNA...what's in a tumor?? junk DNA. Have too much of that and it starts overriding the body's necessary anatomy and physiology.

    So in summary, it's truly a delicate balance between reversing the effects of aging (which is due to DNA degradation) and the effects of tumor surpression (which is often due to a biological ineffectiveness to detect and/or stop faulty cells from replicating)

    Telomerase activity in mature cells which are mature is often indicative of cancer (and increases the likelihood of cancer when artificially induced in mice). I won't delve into the process of mitosis (cellular division/replication, quite the profound process!!)but the thought of an adult cell replicating is nasty! Some muscle cells can be several inches long, imagine one of those trying to replicate WTF!! Neurons have hundreds of thousands of dendrites (the thin arms that branch out from the base to reach other neurons) just imagine the tangled mess that would occur within the nervous system if they tried to replicate LOL!!

    on the contrary amplified telomerase activity in lower order animals such as worms and arthropods does seem to increase longevity though. Regarding the latter phylum arthropoda, these creatures constantly need cellular regeneration if they are going to be molting their exoskeletons in favor of fresher one on a regular basis. And this lifelong telomerase activity is what seems to keep them from not aging throughout life. In fact, it is common for arthropods to die during moulting. They get larger each time, so each moult would require more energy to a point where they simply cannot shed their exoskeleton anymore...now if they evolved a way to stop and stay at a certain size...

    another salient idea to reverse or slow down aging is just implanting stem cells to regenerate new, healthy tissue. This is already a common practice, but it does not seem to be a popular method to isolate stem cells at birth and have them grow in a laboratory for future use. This is similar to what they already do in blood banks. Since I'm blood type O negative, my blood is the most valuable to a blood bank as it is the universal donor blood type. This also means that I am only compatible with type O-. So if I donate to a blood bank enough, they will start storing my own blood for free, for personal use in the event that I may need it.

    anyway...getting waaaaayy off tangent with a bio lesson...nice track

  2. S3C
    Thursday Nov/19/2015

    so which one is better hmmm...probably this (the newer) one. The flow is more energetic, and the ad-libs are more apparent and give the track overall more diversity. although, your quieter vocals are laid back, less strain in your voice makes your tone a tad nicer.

  3. Cyber
    Thursday Nov/19/2015

    Thanks again! Man, that's a lot of science. Interesting reading.

    So one way to achieve immortaly might be to achieve a full-body mutation, that lets cells evade normal cellular senescence? (As in the 'immortalised cell line'?). Interesting life these arthropods live too...

    Stem cells huh. Could you actually prolong your life if you isolate stem cells at birth, is it a working method at this point? If so, do they have to be your own stem cells? I guess storing 'em in a lab for the future might cost a bit. Wonder how all the billionaires in the world might be treating their kids for potential future immortality hmm. Actually watched a South Park episode on stem cell research just recently. I haven't watched South Park in years. What a coincidence!

    That's pretty cool about the personal blood storage! I don't think we have such practices over here though, even if I did have the unusual type. We all have ARh+ if you're pondering.

  4. Cyber
    Thursday Nov/19/2015

    I thought the new one was quieter too? Yeah, might be getting a little to Eminemish on some tracks, more vocal intensity than the themes require. It's all good till the ending hook on this one, those ad-libs... so out of tune... almost makes me make a third version of this... I could call it... Beard. That´d be weird.

    Anyway, appreciate all these comments! (Looks like you missed the first one though. ;)



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